Hitachi announced on November 25, 2016, developed in cell units, high efficiency and high precision analysis of messenger RNA (mRNA) of smaller chips. The product can also master the whole cancer and other human characteristics and the characteristics of each cell, and therefore helps to clarify the pathogenesis of diseases and the development of new treatments.
Hitachi developed tiny microchips, in cells for genetic analysis
Constituted human tissue cells have different characteristics, in order to clarify the pathogenesis of disease, then measuring the mRNA content of each cell. As a means of measuring mRNA, capable of analyzing each cells "single cell analysis technology" cause for concern, but this technology has low accuracy and high cost project.
Hitachi in March 2016, developed integrated 100 can be extracted each cell mRNA 1mm square chip of micro-reactor "Vertical Flow Array Chips." This time, Hitachi in this chip, fills a lot of extracts of mRNA to a micro reactor particles significantly increases its surface area to raise the yield to about 10 times the original. This way, even if only 15 molecules in a cell a trace amount of mRNA can also be extracted simultaneously from up to 100 cells were analyzed.
Configuring multiple chip trial-Hitachi small analytical equipment, and genetic analysis are committed using the prototype device. Results show that with high precision and analyze the genes of about 2000 cells. Hitachi also produced simultaneously to 10,000 cells for gene analysis equipment, in order to accurately grasp the characteristics of human tissue and can be considered valid analysis of thousands of cells at the same time.
The future, Hitachi developed technology will be applied to the analysis of cancer cells and diseases such as cancer cells of the early samples of cells. Verify that it articulated in disease pathogenesis and treatment development in usefulness.
